The Southern Georgian Bay OPP is saying the accident is clear and all northbound lanes are open on Highway 400.
A rolled-over cement truck has the Highway 400 northbound lanes closed around Port Severn.
Police say the crash happened at 8:24 am just south of Honey Harbour Road.
The cause of the collision is still under investigation. The 49-year-old Midland man driving the truck was taken to hospital with non-life-threatening injuries.
The Southern Georgian Bay OPP says the road will remain closed until they can remove the truck safely from the highway. The public will be notified once the highway re-opens.